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2020 Vol.33, Issue 6 Preview Page

Research Article

Biological Activities and Metabolite Analysis of Various Extracts and Fractions from Red Ginseng Marc
Dong Gyu Lee1
,
Ik Soon Jang2
,
Young-Hwa Kang3†
1Graduate Student, Department of Horticulture, Kyungpook National University, Daegu 41566, Korea
2Senior Researcher, Division of Analytical Science Korea Basic Science Institute, Daejeon 34133, Korea
3Professor, Department of Horticulture, Kyungpook National University, Daegu 41566, Korea
*youngh@knu.ac.kr
1 December 2020. pp. 597-603
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Abstract

Red ginseng marc (RGM) has been used on primary industries using fertilizer or forage, and it mostly has been dumped. To improve utilization of RGM, the biological activities of RGM were examined. RGM was extracted and fractionated using various solvents and their biological activities were compared. The hexane fraction from the methanol extract of RGM (RGMMH) showed strong anti-cancer activity (58.56 ± 6.04% at 100 ㎍/mL) and anti-inflammatory effect (65.72 ± 1.33% at 100 ㎍/mL). But, oil extract of RGM extracted with hexane (RGMH) showed low activities (anti-cancer: 16.42 ± 3.33%, at 100 ㎍/mL, anti-inflammatory activity: 29.46 ± 2.10%, at 100 ㎍/mL). Their metabolites were analyzed using HPLC. Panaxydol known as anti-cancer compound of RGM was one of major compounds in RGMMH. Meanwhile, panaxydol was detected in trace amount in red ginseng marc oil (RGMH). In addition, RGMMH and RGMH showed big differences in HPLC profiling. This research suggests optimal extraction method of RGM oil.

Keywords
Anti-cancer
Anti-inflammation
Oil extract
Red ginseng marc
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Information
  • Publisher :The Plant Resources Society of Korea
  • Publisher(Ko) :한국자원식물학회
  • Journal Title :Korean Journal of Plant Resources
  • Journal Title(Ko) :한국자원식물학회지
  • Volume : 33
  • No :6
  • Pages :597-603
  • Received Date : 2020-06-08
  • Revised Date : 2020-07-23
  • Accepted Date : 2020-07-23
  • DOI :https://doi.org/10.7732/kjpr.2020.33.6.597
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