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2020 Vol.33, Issue 3 Preview Page

Research Article

Improving Effects of Brassica oleracea L. var. italica Sprout Extract on Alcoholic Liver Dysfunction
Min Jeong Kim1†
,
Hye Jeong Yang1†
,
Hak Yong Lee2
,
Young Mi Park2
,
Dong Yeop Shin2
,
Yang Hee Lee2
,
Yang Gyu Kang2
,
Tae Su Kim3
,
Sung Pyo Lee3
,
Kwang-Hyun Park45*
1Senior Researcher, Korea Food Research Institute, Wanju 55365, Korea
2Researcher, INVIVO Co. Ltd., Iksan 54538, Korea
3Researcher, Anydoctor HealthCare Co. Ltd., Seoul 08513, Korea.
4Professor, Department of Emergency Medical Rescue and Department of Oriental Pharmaceuticals Development, Nambu University, Gwangju 62271, Korea
5Researcher, Department of Emergency Medicine, Graduate School of Chonnam National University, Gwangju 61469, Korea
* Corresponding Author
† These authors contributed equally to this work.
1 June 2020. pp. 163-169
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Abstract

Alcoholic fatty liver disorder has become a frequent health concern worldwide. To investigate the effects of Brassica oleracea (B. oleracea) sprout extract (BOE), the present study was designed with alcoholic fatty liver in the rat. Initially, the effects of BOE on liver parameters were examined. Male rats were divided into five groups. The normal control group was fed the normal diet, and the BOE group was fed the high fat diet and ethanol with/without BOE for 4 weeks. After 4 weeks feeding period, rats were sacrificed and their livers and blood were used for fatty liver-related biomarkers analyses. As a result, BOE ameliorated fatty liver-related enzymes profiles in liver tissues and also reduced blood alcohol concentration in rat model. We demonstrated that BOE protected the high fat diet and alcohol-induced fatty liver in rat model. Furthermore, BOE increased detoxificative abilities against alcohol.

Keywords
Alcoholic liver dysfunction
Brassica oleracea sprout extract
Fatty liver
High fat diet
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Information
  • Publisher :The Plant Resources Society of Korea
  • Publisher(Ko) :한국자원식물학회
  • Journal Title :Korean Journal of Plant Resources
  • Journal Title(Ko) :한국자원식물학회지
  • Volume : 33
  • No :3
  • Pages :163-169
  • DOI :https://doi.org/10.7732/kjpr.2020.33.3.163
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