• The Beneficial Effect of Platycodon grandiflorum on DSS-induced Colitis through Regulation of HIF-1α in Mice
    Mi-Ok Yang, Noh-Yil Myung
    Ulcerative colitis (UC) is a typical inflammatory colon disorder. Platycodon grandiflorum (PG) is known to exert various beneficial effects including anti-oxidative and … + READ MORE
    Ulcerative colitis (UC) is a typical inflammatory colon disorder. Platycodon grandiflorum (PG) is known to exert various beneficial effects including anti-oxidative and anti-bacterial properties and improvements in liver function. However, the improving effect and mechanism of PG on intestinal inflammation are not fully understood. The present research was designed to investigate the effect of PG on the clinical signs of DSS-induced colitis in mice. The ameliorative effects of PG on inflammatory cytokine expression and the activation of hypoxia-inducible-factor (HIF)-1α in DSS-treated colon tissue were also determined. Our results showed that mice treated with DSS displayed the main clinical symptoms of colitis, including weight loss, bloody stools, decrease in colon length and diarrhea and PG treatment significantly improved the clinical features induced by DSS in mice. PG inhibited the increase in the levels of inflammatory cytokines caused by DSS in colon tissues. We also showed that the anti-inflammatory mechanism of PG involved suppressing the activation of HIF-1α in DSS-treated colon tissues. Collectively, the findings of this study indicate the prospect of developing new drugs from PG for UC treatment. - COLLAPSE
    1 June 2022
  • Seasonal Variation of Rubber Production in Russian Dandelion, Taraxacum kok-saghyz, Grown in Korea
    Sandeep Kumar Tata, Seung Baek Hong, Sung Woo Bae, Jong-Chan Park, Stephen Beungtae Ryu
    Russian dandelion, Taraxacum kok-saghyz L.E.Rodin, is an important alternative source of natural rubber. Thus, it is critical to identify the best season … + READ MORE
    Russian dandelion, Taraxacum kok-saghyz L.E.Rodin, is an important alternative source of natural rubber. Thus, it is critical to identify the best season for natural rubber production and harvesting for this species. In this study, T. kok-saghyz was grown in experimental fields in Korea to check the variation in rubber content with the change in the season. Studies using T. kok-saghyz plants indicate that spring and autumn are the best seasons for rubber accumulation. For several reasons, our study suggests that planting in autumn and harvesting in late spring is the best strategy for economic cultivation in Korea. Our data will be useful for future commercialization of rubber production from T. kok-saghyz because time will be saved if the plant is grown and harvested in the optimum season. - COLLAPSE
    1 June 2022
  • New Report of Vicia grandiflora Scop. in Korea
    Young Jong Jang, Kang-Hyup Lee, Eun Su Kang, Beom Kyun Park, Dong Chan Son
    We have discovered Vicia grandiflora Scop., a newly invasive alien species in Baekun-ri, Okcheon-gun, Chungcheongbuk-do, Korea. This species is native to regions … + READ MORE
    We have discovered Vicia grandiflora Scop., a newly invasive alien species in Baekun-ri, Okcheon-gun, Chungcheongbuk-do, Korea. This species is native to regions from Central and Southeast Europe to Central Asia and Iran and is reported as an invasive species in North America and Japan. This species is similar to the Vicia sativa complex (V. sativa subsp. sativa, V. sativa subsp. nigra) but can be readily distinguished by the undivided ovate to semi-hastate stipules of the upper leaves, yellowish petals, large size of its flower, and elongated hilum. In the field, V. grandiflora grows in disturbed sites near cultivated land, suggesting that their seeds are typically transported by vehicles along with fertilizer or livestock feed. Here, we present the morphological description, photographs, and sites of V. grandiflora growth, which will be useful in guiding the management of this invasive alien plant. - COLLAPSE
    1 June 2022