Whitening and Antioxidant Effects of Extracts from Angelica gigas Nakai Thin Root

Sang-Hoon Lee; Jeong-Yong Park; Kyung Hye Seo; Jang Nam Choi; Yoon-Jeong Lee; Youn-Ho Moon; Mok Hur; Woo Tae Park; Yun Chan Huh; Jae-Ki Chang; Sung Cheol Koo

doi:10.7732/kjpr.2021.34.1.037

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2021 Vol.34, Issue 1 Preview Page Next Page

Research Article

Whitening and Antioxidant Effects of Extracts from Angelica gigas Nakai Thin Root 참당귀 세미 추출물의 미백 및 항산화 효과

1 February 2021. pp. 37-43

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Abstract

Angelica gigas Nakai (AGN) is a perennial plant belonging to the family Apiaceae. Its root has been utilized as a traditional medicine especially in Korea. This study was carried out to evaluate the potential use of extracts from AGN root parts as a cosmetic material. The dried AGN roots are divided into body (B), thick root (TkR), medium root(MR) and thin root (TnR) according to their diameter before cutting into medicine. B, TkR and MR of AGN are combined and used as medicinal herbs (MH). The extracts from AGN each root part (B, TkR, MR, TnR, MH) were used to test the effect on cell viability using MTS assay and to examine inhibitory effect on melanin accumulation in B16F10 melanoma cells. All extracts (50 - 200 ㎍/mL) from the each root part did not affect the cell viability. And inhibitory effect of all root extracts (200 ㎍/mL) on melanin accumulation was 12-19%. Especially, TnR showed similar inhibitory effect on melanin accumulation to MH. In addition, DPPH and ABTS free radical scavenging activity were higher in the TnR extract compared to MH. This study showed that the TnR extract exhibit high inhibitory effect on melanin accumulation and antioxidant activity compared to MH, suggesting that TnR extract has potential as a cosmetic ingredient.

Keywords

Angelica gigas Nakai

Antioxidant activity

Melanin

Thin root

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Information

Publisher :The Plant Resources Society of Korea
Publisher(Ko) :한국자원식물학회
Journal Title :Korean Journal of Plant Resources
Journal Title(Ko) :한국자원식물학회지
Volume : 34
No :1
Pages :37-43
Received Date : 2020-09-07
Revised Date : 2020-11-20
Accepted Date : 2020-11-30
DOI :https://doi.org/10.7732/kjpr.2021.34.1.037

Korean Journal of Plant Resources ISSN:1226-3591(Print) 2287-8203(Online) 한국자원식물학회지

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